2026 Pediatric Update (On-Demand)-Dr. Lee Presentation Atopic Dermatitis

Video Transcription

Video Summary

The 2023 atopic dermatitis guideline updates the 2012 version and focuses on five questions: topical therapy, elimination diets, bleach baths, allergen immunotherapy, and systemic treatments. Recommended topical options include topical corticosteroids, topical calcineurin inhibitors, occlusive/wet-wrap therapy for recalcitrant lesions, and crisaborole for mild-moderate disease. The guideline advises against prescription moisturizers, topical JAK inhibitors like ruxolitinib, and topical antimicrobials. It recommends proactive maintenance therapy on flare-prone areas. Elimination diets are discouraged. Dilute bleach baths are suggested only for moderate-severe disease, not mild disease. Allergen immunotherapy may help moderate-severe atopic dermatitis, especially with dust mite sensitization, but is not recommended for mild disease. For systemic therapy in moderate-severe cases, options include dupilumab, tralokinumab, oral JAK inhibitors, cyclosporine, and narrow-band UVB; systemic steroids, azathioprine, methotrexate, mycophenolate, and low-dose baricitinib are discouraged.

Keywords

atopic dermatitis

topical therapy

elimination diets

allergen immunotherapy

systemic treatments