A Holistic & Practical Approach for Addressing Opioid Substance Use Disorder-Samuel

Video Transcription

Video Summary

The transcript introduces medications for treating opioid use disorder (OUD), emphasizing that OUD is a clinically significant pattern of opioid use causing impairment or distress. Diagnosis requires at least two DSM-5 criteria within 12 months, such as tolerance, withdrawal, difficulty cutting down, or major life disruption. The speaker stresses that medication-assisted treatment (MAT) combined with behavioral therapy is more effective than quitting “cold turkey” or using counseling alone, with benefits including reduced misuse, better treatment retention, improved adherence, and lower mortality. Key medications discussed are buprenorphine, methadone, and naltrexone, with clonidine and lofexidine used mainly for withdrawal symptoms. The lecture focuses on buprenorphine, especially buprenorphine/naloxone (Suboxone), explaining its partial agonist action, ceiling effect, reduced respiratory depression, and how naloxone helps prevent misuse. It also covers initiation timing, dosing, side effects, monitoring, precautions, and tapering recommendations.

Asset Caption

Dr. Samuel Buprenorphine Recording

Keywords

opioid use disorder

medication-assisted treatment

buprenorphine

Suboxone

naloxone

withdrawal management